The President's children have been kidnapped. Detective Alex Cross is investigating the shocking crime, but someone powerful is trying to keep him off the case. Just days later, a deadly contagion in the DC water supply threatens to cripple the capital, and Cross fears that the stakes are much higher than he first thought - America is under attack. If Cross stands a chance of finding the missing children and preventing an event that could change the fate of the nation, he must make a desperate decision that goes against everything he believes in.