A series of horrific murders seem disturbingly familiar to Detective Jane Rizzoli. They remind her and Forensic Pathologist Maura Isles of those committed by a killer known as The Surgeon, who they recently put behind bars. While they're still trying to track down the new killer, the unthinkable happens: The Surgeon escapes. Suddenly, Jane is chasing not one but two brilliant and twisted minds, united by one goal... To perfect their skills on the woman who's hunting them.