'She understands Karma, she says: "What I do, I reap"' Her name means sadness, yet Tristessa, a prostitute and morphine addict, lives without cares in her shabby room with a menagerie of pets and an altar to the Virgin Mary. Based on Jack Kerouac's own real-life love affair in Mexico city, this is the story of a man's ill-fated relationship with a woman he portrays with tenderness and dignity, even as her life spirals out of control.